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Vardenafil hydrochloride trihydrate

CAS No. 330808-88-3

Vardenafil hydrochloride trihydrate ( BAY 38-9456;Vardenafil HCl; Levitra; Staxyn; Vivanza )

Catalog No. M18429 CAS No. 330808-88-3

Vardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 Get Quote
10MG 58 Get Quote
25MG 114 Get Quote
50MG 177 Get Quote
100MG 282 Get Quote
200MG 421 Get Quote
500MG 678 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Vardenafil hydrochloride trihydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Vardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
  • Description
    Vardenafil, also known as BAY 38-9456, is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil (VAR) is synthetic, highly selective, and potent inhibitor of phosphodiesterase-5 which competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. It is clinically approved for treatment of erectile dysfunction in men, including diabetic and postprostatectomy patients.
  • Synonyms
    BAY 38-9456;Vardenafil HCl; Levitra; Staxyn; Vivanza
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PDE1; PDE5
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    330808-88-3
  • Formula Weight
    579.11
  • Molecular Formula
    C23H32N6O4S·HCl·3H2O
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    n12[nH]c(nc(=O)c1c(nc2CCC)C)c1c(ccc(c1)S(=O)(=O)N1CCN(CC1)CC)OCC.Cl.O.O.O
  • Chemical Name
    2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one dihydrochloride trihydrate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1 Saenz de Tejada I, et al. Int J Impot Res, 2001, 13(5), 282-290.
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